Cold Plasma Sterilization of Open Wounds: Live Rat Model

نویسندگان

  • Danil Dobrynin
  • Kimberly Wasko
  • Gary Friedman
  • Alexander Fridman
  • Gregory Fridman
چکیده

Atmospheric pressure non-equilibrium (cold) plasmas are already known to be effective sterilization agents. This work further confirms the ability of cold plasma to inactivate pathogenic organisms in a live animal model. The rat wound model used here represents a surgical treatment situation whereby the wound is open and the bleeding is controlled. High concentration of Staphylococcus aureus is placed onto the wound area and allowed to incubate for four hours prior to cold plasma treatment. We show a 3-log reduction in pathogen load on the wound following a one minute treatment.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Surface Decontamination by Dielectric Barrier Discharge Plasma

Background: Dielectric barrier discharge (DBD), a source of non-thermal plasma, is used in surface decontamination. Objective: To study the effect of DBD plasma treatment, we evaluated the effect of plasma exposure time on inactivation of Bacillus subtilis. Results: Applying the DBD plasma to the culture of B. subtilis caused complete sterilization of the surface without any thermal effects. In...

متن کامل

Microbial Decontamination of Spices Using Cold Plasma

Most of spices are produced using traditional systems. In unsanitary conditions, spices can contain large numbers of pathogenic microbes such as bacteria, molds and yeasts. Some microorganisms are known as human pathogens, which need disinfection mechanisms that minimize their potential harms to active substances in spices. Use of contaminated spices in foods can significantly decrease the shel...

متن کامل

Assessment of anti-bacterial activity of non-thermal plasma in sterilization of infectious wastes

In today's world, the production of hospital wastes and their adverse effects such as infectious outbreaks and resistance to treatment is an important issue. Therefore, it's vital to find a new and efficient method to manage such wastes. In this study, the ability of dielectric barrier discharge (DBD) plasma to deactivate Pseudomonas aeruginosa and Staphylococcus aureus bacter...

متن کامل

Management of Large Chronic Non-healing Wounds by Autogenous Platelet Rich Plasma and Reconstructive Surgery in Three Cats

Case Description- Three domestic short haired cats (2, 5 and 4 years of age) were presented to the Madras Veterinary College Teaching Hospital, with the history of large chronic, full thickness wounds on the right lateral cervical, left caudal forearm and right lateral thoracic region respectively. Etiology of the wounds was trauma in two cases and thermal burns in the third ca...

متن کامل

Plasma medicine: possible applications in dermatology.

As a result of both the better understanding of complex plasma phenomena and the development of new plasma sources in the past few years, plasma medicine has developed into an innovative field of research showing high potential. While thermal plasmas have long been used in various medical fields (for instance for cauterization and sterilization of medical instruments), current research mainly f...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011